NEW AND INSIGHTFUL

GLYCOLISIS:

   Glycolysis also known as Embden-Meyerhof pathway is the first step in the catabolism of glucose through respiration and fermentation (Bauman Robert, 2012). It involves the dividing of a molecule containing 6-carbon glucose into two three-carbon sugar molecules. The end-product of glycolysis is 2 pyruvic acid and release of stored energy in ATP (Adenosine Triphosphate). Glycolysis is an anaerobic process.

Figure 1 Glycolysis

COMPETITIVE and NONCOMPETITIVE INHIBITORS:

Competitive inhibitors are inhibitory substances that block enzymatic activity by blocking active site. They fit on site and prevent the binding of substrate. These inhibitors can either bind permanently resulting in the loss of enzymatic activity or reversibly by increasing concentration of substrate which increases the likelihood of binning site being filled with substrate instead of inhibitors (Bauman Robert 2011).

Noncompetitive inhibitors also known as allosteric inhibitors bind to allosteric site on any part of the cell which changes the shape of the active site and making the substrate unable to bind. Excitatory allosteric inhibitors occur when an activator molecule binds to an allosteric site and changes the active site, thus capable of binning substrate (Bauman Robert 2011).

Figure 2 Competitive and noncompetitive inhibitors

ENZYME:

An enzyme is an organic catalyst. In order to understand enzymes one need to know the definition of a catalyst which is a chemical that increases the likelihood of a reaction but is not permanently changed. Enzymes acts on molecules called substrate. Enzymes can be classified into six categories based on their reaction types (Bauman Robert 2011).

Figure 3 Enzyme

REFERENCES:

Bauman RW. Microbiology with disease by Taxonomy. 3rd ed. San Francisco (CA): Pearson; 2011.

http://www.tutorialz360.com/inhibitors/ (FIGURE 3)

http://students.cis.uab.edu/clight/whatisenzyme.jpg (FIGURE 2)

https://encrypted-tbn2.gstatic.com/images?q=tbn:ANd9GcQJBMB9pxJCIQoXJCgkxh2Dgn7TyILs9aa7TxyO9qkX0ZeKtd2p(FIGURE 1)